Detalhe da pesquisa
1.
Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner.
Cell
; 180(5): 833-846.e16, 2020 03 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32142677
2.
The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation.
Immunity
; 56(5): 979-997.e11, 2023 05 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37100060
3.
Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells.
Nat Immunol
; 18(1): 74-85, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27893700
4.
Constitutive Activation of gp130 in T Cells Results in Senescence and Premature Aging.
J Immunol
; 210(11): 1641-1652, 2023 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37058108
5.
Cell-Autonomous Constitutive gp130 Signaling in T Cells Amplifies TH17 Cell Responses and Causes Severe Lung Inflammation.
J Immunol
; 210(11): 1717-1727, 2023 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37058116
6.
Treatment of type 2 diabetes with the designer cytokine IC7Fc.
Nature
; 574(7776): 63-68, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31554967
7.
Blockade of the protease ADAM17 ameliorates experimental pancreatitis.
Proc Natl Acad Sci U S A
; 119(42): e2213744119, 2022 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36215509
8.
Cross-talk between IL-6 trans-signaling and AIM2 inflammasome/IL-1ß axes bridge innate immunity and epithelial apoptosis to promote emphysema.
Proc Natl Acad Sci U S A
; 119(36): e2201494119, 2022 09 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36037355
9.
Corrigendum: Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells.
Nat Immunol
; 18(4): 474, 2017 03 22.
Artigo
Inglês
| MEDLINE | ID: mdl-28323263
10.
The metalloprotease ADAM10 generates soluble interleukin-2 receptor alpha (sCD25) in vivo.
J Biol Chem
; 298(6): 101910, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35398356
11.
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway.
Mol Cancer
; 22(1): 133, 2023 08 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37573301
12.
Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate.
Blood
; 137(10): 1392-1405, 2021 03 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32932519
13.
An epithelial gene signature of trans-IL-6 signaling defines a subgroup of type 2-low asthma.
Respir Res
; 24(1): 308, 2023 Dec 07.
Artigo
Inglês
| MEDLINE | ID: mdl-38062491
14.
Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation.
Circ Res
; 129(8): 804-820, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34433292
15.
Interleukin-6 controls recycling and degradation, but not internalization of its receptors.
J Biol Chem
; 296: 100434, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33610555
16.
Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling.
J Hepatol
; 77(6): 1631-1641, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35988690
17.
Therapeutic Interleukin-6 Trans-signaling Inhibition by Olamkicept (sgp130Fc) in Patients With Active Inflammatory Bowel Disease.
Gastroenterology
; 160(7): 2354-2366.e11, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33667488
18.
Macrophage-derived IL-6 trans-signalling as a novel target in the pathogenesis of bronchopulmonary dysplasia.
Eur Respir J
; 59(2)2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34446466
19.
A role for IL-27p28 as an antagonist of gp130-mediated signaling.
Nat Immunol
; 11(12): 1119-26, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-21057510
20.
Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN.
Blood
; 136(18): 2051-2064, 2020 10 29.
Artigo
Inglês
| MEDLINE | ID: mdl-32726410